Stable credit card processing for research peptide suppliers. Manual underwriting, dedicated MIDs, and bank relationships built for the long term, not automated approvals that terminate six months in.
Every feature below is standard across our peptide business merchant accounts. Not an upgrade tier. This is payment processing for peptides built as a core category, not a workaround.
Visa and Mastercard peptide credit card processing, with each card network confirmed by the acquiring bank per compound before your account goes live. Not a shared aggregator account.
Cryptocurrency and ACH bank transfer settlement available. Preferred by international peptide merchants who require alternative payout options.
Payments processed directly on your site. No redirects, no third-party checkout pages. Works with Shopify, WooCommerce, and custom storefronts.
T+1 payout available for established accounts. T+3 or weekly for accounts building processing history. Settlement schedule confirmed before go-live.
Access to 30+ acquiring institutions. Multi-MID arrangements available for volume redundancy and improved payment continuity.
Reserve percentage negotiated individually and confirmed in writing at approval. Rolling release structure for merchants with established processing history.
CERF provides payment processing for research-only peptide businesses operating in compliance with applicable law. All merchants are required to maintain clear research-only disclaimers on their website, comply with applicable labelling standards, and ensure their business model is structured for research supply only. CERF does not support businesses selling peptides for human consumption or making therapeutic claims.
Card networks assess risk at the category level. Research peptide businesses receive an elevated classification by default, applied to the product type rather than the individual business. Processors without specific underwriting frameworks for this category apply blanket restrictions across the board. A clean processing history does not change the classification.
A specialist peptide payment processor provides a dedicated account specifically underwritten for research peptide businesses. Unlike mainstream processors, the acquiring bank reviews your business before you go live, so fees, reserve terms, and settlement schedules are agreed upfront. There are no post-approval surprises.
Approved in 20 minutes. Payments flow normally. Revenue grows. Six months later, an automated review flags the business.
Peptide account terminated. No appeal. No processing.
This is not a manual decision. It is an automated flag triggered by the merchant category, transaction patterns, or a product name match against the processor's restricted list. PayPal and Square apply the same restrictions.
CERF is a specialist peptide payment processor for research-only businesses: a dedicated merchant account with a specialist acquiring bank, not a payment facilitator account subject to automated closures.
Why mainstream processors are not a long-term solution for high-risk peptide payment processing.
| Traditional Processor | CERF | |
|---|---|---|
| Underwriting | Automated, 20 minutes | Manual, reviewed before approval |
| Peptide businesses | Explicitly prohibited | Supported, core underwritten category |
| When risk is assessed | Six months in, during a volume review | Before your account opens |
| Account stability | Terminated without notice | Dedicated MID, not a shared account |
| Reserve | Funds held without warning, no formal terms | Reserve agreed in writing at approval |
| LegitScript required | Required | Not required for research-only businesses |
| Volume capacity | Flagged or terminated at scale | $5M+/month. Structured for large-scale peptide operations. |
Risk is front-loaded. Every material decision is made before your account opens, not six months later during an automated review.
Every application reviewed by a person, not an automated risk model. We assess your business individually against acquiring requirements specific to the peptide category.
Each compound confirmed with the acquiring bank before your account opens. No compounds are assumed. Each one is explicitly approved as part of the underwriting process.
Risk is assessed before go-live, not six months in during a volume review. If there is an issue with your business model or website, you find out before your account is active.
If your website needs changes to meet acquiring requirements, you receive specific recommendations before go-live, not a rejection after the fact.
Relationships with 30+ acquiring institutions, not a single peptide payment processor dependency. Redundancy built in from the start, with multi-MID setups available for higher-volume merchants.
Reserve percentage, settlement schedule, and processing fee confirmed in writing before approval. No surprises after you go live.
Merchants terminated by Stripe or PayPal are sometimes added to the MATCH list. A MATCH listing does not automatically disqualify a peptide business from specialist acquiring. CERF reviews each case individually. Most compliant research-only businesses with prior terminations are approvable once the processing history and termination context are assessed in full.
CERF provides peptide merchant services across the full range of research peptide business models: direct-to-consumer ecommerce, wholesale distribution, specialty catalogues, and established high-volume operations processing $5M+ monthly.
Research peptide ecommerce brands selling through Shopify, WooCommerce, or custom websites. Embedded checkout, descriptor management, and chargeback monitoring included.
Established research peptide businesses processing $5M+ monthly. Multi-MID structure, dedicated acquiring relationships, and reserve optimisation for operations where payment continuity directly impacts revenue.
Bulk research-only peptide supply with B2B ordering, recurring buyers, and high-ticket transactions. Multi-MID structure available for volume distribution across multiple acquiring relationships.
Businesses focused on research-only GLP-1 related products. Semaglutide merchant processing and tirzepatide research accounts assessed individually by jurisdiction and product positioning at underwriting.
Merchants offering broad research peptide catalogues including BPC-157, TB-500, CJC-1295, Ipamorelin, and related compounds. Per-compound confirmation included in underwriting.
Research peptide businesses shipping to the US, EU, UK, and international markets simultaneously. Multi-currency acquiring and jurisdiction-specific compliance for merchants operating across borders.
Research and wellness brands carrying nutraceutical product lines alongside peptide compounds may also require a nutraceuticals merchant account with a separate MCC configuration. Businesses offering subscription-based research programmes should review our subscription billing merchant account structure before applying.
CERF processes the following research peptide categories. Each compound, including BPC-157 merchant account applications and GLP-1 compounds, is confirmed individually with the acquiring bank before the account goes live. Businesses seeking a GLP-1 payment processor for peptides are assessed individually based on jurisdiction and product positioning.
The most common reason peptide merchants are declined is non-compliant website copy, not their product category. If your site clearly positions products for research use only and avoids health claims, approval through a specialist acquirer is typically straightforward. The package below reflects the standard peptide merchant underwriting documentation for US entities, CERF places European, UK, Canadian, and other international peptide businesses on an equivalent basis, with the specific documents confirmed at application.
The pre-application form, completed in full, is the starting point for underwriting review.
A clear photo of the business owner's driver's license, passport, or national ID, used to confirm identity.
A voided check or a bank letter confirming the business's settlement account.
A completed W-9 and EIN confirmation letter for US entities, or the equivalent tax registration and identification documents for businesses registered elsewhere.
Legal formation documents confirming the entity and its structure.
Proof of domain registration for the business website.
The most recent 3 months of business or personal bank statements.
The most recent 3 months of processing statements, if the business has prior processing history. Prior termination does not disqualify you.
Three structured stages from application to active processing. Every decision is made before your account goes live.
Complete the contact form with your business details, product category, and estimated monthly volume. A peptide account specialist will review your submission and be in touch to discuss next steps.
We review your website, disclaimers, chargeback history, compound list, and processing setup. For most research peptide merchants, this stage takes up to 5 business days.
Once approved, your peptide payment gateway connects to your checkout. We support Shopify, WooCommerce, and custom integrations. Processing begins following gateway integration and final bank confirmation.
All fees and terms are disclosed before signing. Rates and terms below are representative for each solution. Exact terms, including any additional account fees and the specific checkout flow, are confirmed once a merchant is approved and matched with a processing solution. Settlement is never routed through an account CERF controls, funds move directly from the acquiring bank or licensed on-ramp partner to the merchant's own bank account or wallet.
The full card solution makes CERF your peptide credit card processor through a regular domestic bank account structure. It operates like a standard merchant account, with checkout fully customizable through the payment gateway provided. Details on this solution and its requirements follow below.
| Term | What to Expect |
|---|---|
| Rate | 6.5% to 8.95% |
| Reserve | 0% is achievable for research peptide merchants with a clean processing history. The acquiring bank may require a reserve, typically 5% to 10%, if chargeback activity or risk profile changes. |
| Transaction fee | $0.45 |
| Chargeback fee | $35 |
| Settlement / payout | Within 72 hours |
| Accepted at checkout | All major card brands |
| Integrations | Shopify, WooCommerce, custom APIs |
Customers pay at checkout using Visa, Mastercard, Apple Pay or Google Pay, just like a standard card transaction. Payment is processed by a licensed crypto on-ramp provider, with proceeds settled directly to the merchant's Polygon wallet in stablecoin.
| Term | What to Expect |
|---|---|
| Rate | 4% to 6% |
| Reserve | 0% |
| Minimum processing volume | None |
| Transaction fee | $0 |
| Chargeback fee | $0 |
| Settlement / payout | Approximately 60 to 90 seconds, settled as stablecoin (such as USDC or USDT) to the merchant's Polygon wallet, with no holding period |
| Accepted at checkout | Visa, Mastercard, Apple Pay, Google Pay and more, depending on the on-ramp provider assigned |
| Integrations | Shopify, WooCommerce, custom APIs |
The on-ramp above serves US based customers. For merchants with customers outside the United States, CERF works with additional on-ramp partners, including Ramp, Transak, Banxa, Guardarian, Bitnovo, Cryptix, Unlimit, Utorg, Kryptonim and others, each supporting a different mix of cards and payment methods depending on the customer's region. The right on-ramp, or combination of on-ramps, is matched to the merchant's customer base at approval.
As a peptide ACH processor, CERF settles the ACH solution as a direct bank to bank transfer, a straightforward option for merchants who want lower processing costs. Same Day ACH is available for qualifying accounts.
| Term | What to Expect |
|---|---|
| Rate | 3.95% |
| Reserve | 0% |
| Transaction fee | $0.30 |
| Chargeback fee | Not applicable, ACH disputes are handled as returns, not chargebacks |
| Monthly fee | $150 |
| Same Day ACH | Available for qualifying accounts, confirmed at approval |
| Accepted at checkout | Direct bank to bank transfer |
| Integrations | Shopify, WooCommerce, custom APIs |
The global peptide therapeutics market was valued at $52.6 billion in 2025 and continues to grow as pharmaceutical development and consumer interest in peptide-based compounds accelerates. The driver most visible to payment processors is the GLP-1 category: semaglutide now generates over 1.5 million monthly searches in the United States alone, compared to approximately 74,000 for BPC-157, one of the most widely searched research peptides. That gap is closing.
For payment processors, this growth creates a specific challenge. The same consumer awareness driving demand also increases the scrutiny applied to peptide businesses by card networks and acquiring banks. Merchants who grew steadily through 2022 and 2023 increasingly found their accounts reviewed, restricted, or terminated as processor risk models were updated to reflect the higher-profile nature of the category.
In February 2026, fourteen of nineteen peptides previously under FDA compounding restrictions were reclassified back to Category 1 status, reinstating their availability through licensed compounding pharmacies. This current regulatory landscape for peptide compounding reflects the ongoing evolution of the space and underscores why payment infrastructure built on static risk models consistently fails peptide merchants over time. Stable processing in this vertical requires a processor who tracks these changes, not one who discovers them after terminating an account.
CERF has been building payment processing for peptides since 2022 and has adapted its underwriting alongside these changes, working with acquiring partners who have developed specific frameworks for research-only peptide merchants rather than treating them as generic nutraceutical businesses.
CERF is the payment processor for peptides that combines manual underwriting, dedicated MIDs, and flexible settlement, from peptide credit card services to ACH and crypto. Applications are reviewed individually.